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ASSESSING THE EFFECT OF NEGLECTED TROPICAL DISEASE ON THE TRANSMISSION OF PLASMODIUM FALCIPARUM IN AN AREA OF CO-ENDEMICITY

The main objectives of the project is to assess the effect of S. haematobium infection on malaria transmission. The idea is to assess whether S. haematobium infection expands the human reservoir of P. falciparum. Secondly, to assess whether S. haematobium infection increases transmission of P. falciparum gametocytes from co-infected subjects to mosquitoes. And finally, to assess whether S. haematobium infection can affect the probability of transmission of P. falciparum from mosquitos to human. The results generated by this study will be relevant for policy makers working in the field of malaria and it will increase our knowledge on helminths and its impact on the immune response. The plan is to provide significant knowledge to the efforts of eliminating malaria globally targeting factors influencing its transmission.